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670 GENES FOUND

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Gene

 

 

Gene description

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Protein class

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Tissue

Cell

Pathology

 

 

 

 

 

 

Subcellular location

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Prognostic p-value

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RNA tissue category

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METMET proto-oncogene, receptor tyrosine kinaseCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
RAS pathway related proteins
Plasma membrane
Cytosol		Pancreatic cancer: 1.21e-7
Head and neck cancer: 6.75e-4
Mixed
MYEOVMyeloma overexpressedPredicted membrane proteins
Nucleus
Vesicles		Pancreatic cancer: 1.54e-7
Renal cancer: 1.48e-5
Lung cancer: 2.00e-4
Group enriched
EPS8Epidermal growth factor receptor pathway substrate 8Disease related genes
Plasma proteins
Predicted intracellular proteins
Golgi apparatusRenal cancer: 1.45e-7
Pancreatic cancer: 3.33e-7
Thyroid cancer: 5.11e-4
Mixed
ZNF488Zinc finger protein 488Predicted intracellular proteins
Predicted secreted proteins
Nucleoplasm
Cytosol		Pancreatic cancer: 4.02e-7
Group enriched
KPNA4Karyopherin alpha 4 (importin alpha 3)Predicted intracellular proteins
Transporters
NucleusLiver cancer: 6.24e-7
Pancreatic cancer: 1.03e-6
Endometrial cancer: 8.59e-4
Expressed in all
FZD6Frizzled class receptor 6Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins
Plasma membranePancreatic cancer: 1.20e-6
Mixed
LY6DLymphocyte antigen 6 complex, locus DPlasma proteins
Predicted membrane proteins
Pancreatic cancer: 1.94e-6
Renal cancer: 1.20e-4
Group enriched
ANLNAnillin actin binding proteinDisease related genes
Predicted intracellular proteins
NucleoplasmRenal cancer: 0.00e+0
Liver cancer: 5.97e-7
Pancreatic cancer: 2.00e-6
Lung cancer: 6.99e-5
Endometrial cancer: 1.73e-4
Tissue enhanced
INSIG2Insulin induced gene 2Predicted membrane proteins
Pancreatic cancer: 2.19e-6
Renal cancer: 4.11e-6
Head and neck cancer: 7.10e-4
Expressed in all
ARMC10Armadillo repeat containing 10Predicted intracellular proteins
Predicted membrane proteins
MitochondriaPancreatic cancer: 2.49e-6
Glioma: 6.98e-6
Liver cancer: 3.58e-4
Expressed in all
WNT7AWingless-type MMTV integration site family, member 7ADisease related genes
Plasma proteins
Predicted secreted proteins
Pancreatic cancer: 3.03e-6
Endometrial cancer: 2.96e-5
Tissue enhanced
CHEK1Checkpoint kinase 1Cancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Vesicles		Renal cancer: 1.04e-8
Pancreatic cancer: 3.10e-6
Liver cancer: 3.70e-6
Colorectal cancer: 3.62e-4
Tissue enhanced
MRPL3Mitochondrial ribosomal protein L3Disease related genes
Predicted intracellular proteins
Ribosomal proteins
Liver cancer: 4.33e-7
Pancreatic cancer: 3.51e-6
Ovarian cancer: 1.36e-4
Expressed in all
LAMA3Laminin, alpha 3Disease related genes
Predicted intracellular proteins
Predicted secreted proteins
Endoplasmic reticulum
Vesicles
Cytosol		Pancreatic cancer: 3.58e-6
Mixed
COMMD2COMM domain containing 2Predicted intracellular proteins
Nucleoplasm
Nuclear bodies		Pancreatic cancer: 3.69e-6
Liver cancer: 2.78e-4
Expressed in all
ZFP91ZFP91 zinc finger proteinPredicted intracellular proteins
Transcription factors
Nucleus
Nucleoli		Pancreatic cancer: 3.74e-6
Expressed in all
CA12Carbonic anhydrase XIIDisease related genes
Enzymes
Potential drug targets
Predicted membrane proteins
Nucleus
Vesicles		Pancreatic cancer: 3.80e-6
Tissue enhanced
CDK6Cyclin-dependent kinase 6Cancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Cytosol		Pancreatic cancer: 3.86e-6
Urothelial cancer: 2.33e-5
Mixed
AHNAK2AHNAK nucleoprotein 2Cancer-related genes
Predicted intracellular proteins
Plasma membrane
Cytosol		Pancreatic cancer: 4.05e-6
Urothelial cancer: 2.23e-5
Lung cancer: 2.79e-5
Tissue enriched
JAG1Jagged 1CD markers
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Golgi apparatus
Plasma membrane		Pancreatic cancer: 4.10e-6
Expressed in all
RACGAP1Rac GTPase activating protein 1Predicted intracellular proteins
NucleoplasmRenal cancer: 3.98e-8
Liver cancer: 1.86e-6
Pancreatic cancer: 4.12e-6
Breast cancer: 1.51e-4
Tissue enhanced
CDK1Cyclin-dependent kinase 1Cancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins
Transporters
Nucleus
Cytosol		Renal cancer: 0.00e+0
Liver cancer: 1.10e-6
Pancreatic cancer: 4.15e-6
Lung cancer: 7.88e-4
Cervical cancer: 8.81e-4
Mixed
CCNA2Cyclin A2Cancer-related genes
Predicted intracellular proteins
Nucleoplasm
Cytosol		Renal cancer: 0.00e+0
Pancreatic cancer: 4.43e-6
Liver cancer: 9.17e-5
Lung cancer: 4.27e-4
Endometrial cancer: 8.78e-4
Mixed
GPR87G protein-coupled receptor 87G-protein coupled receptors
Predicted membrane proteins
Nucleoplasm
Lipid droplets
Mitochondria		Pancreatic cancer: 4.62e-6
Tissue enhanced
GPRC5AG protein-coupled receptor, class C, group 5, member AG-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Vesicles
Plasma membrane		Pancreatic cancer: 4.63e-6
Renal cancer: 9.02e-5
Tissue enhanced
FAM83AFamily with sequence similarity 83, member APredicted intracellular proteins
NucleoplasmLung cancer: 2.98e-9
Pancreatic cancer: 4.99e-6
Endometrial cancer: 3.85e-4
Tissue enriched
RIPK2Receptor-interacting serine-threonine kinase 2Enzymes
Predicted intracellular proteins
CytosolRenal cancer: 0.00e+0
Pancreatic cancer: 5.00e-6
Lung cancer: 6.33e-5
Urothelial cancer: 8.05e-4
Mixed
ITGB6Integrin, beta 6Cancer-related genes
Disease related genes
Plasma proteins
Predicted membrane proteins
Nucleoplasm
Cell Junctions
Centrosome		Pancreatic cancer: 5.03e-6
Tissue enhanced
ARNTL2Aryl hydrocarbon receptor nuclear translocator-like 2Predicted intracellular proteins
Transcription factors
Nucleus
Nucleoli		Pancreatic cancer: 5.29e-6
Renal cancer: 1.56e-5
Tissue enhanced
PLA2G16Phospholipase A2, group XVIEnzymes
Predicted intracellular proteins
Predicted membrane proteins
RAS pathway related proteins
MitochondriaPancreatic cancer: 5.58e-6
Thyroid cancer: 2.54e-5
Expressed in all
TUBA1CTubulin, alpha 1cPlasma proteins
Predicted intracellular proteins
MicrotubulesLiver cancer: 8.48e-8
Renal cancer: 6.26e-7
Pancreatic cancer: 5.64e-6
Colorectal cancer: 7.37e-5
Breast cancer: 2.90e-4
Lung cancer: 6.85e-4
Expressed in all
SERPINB5Serpin peptidase inhibitor, clade B (ovalbumin), member 5Plasma proteins
Predicted intracellular proteins
VesiclesPancreatic cancer: 5.71e-6
Lung cancer: 1.54e-4
Group enriched
SLC35F2Solute carrier family 35, member F2Predicted membrane proteins
Transporters
MitochondriaPancreatic cancer: 5.92e-6
Lung cancer: 4.03e-4
Glioma: 7.31e-4
Mixed
RARRES3Retinoic acid receptor responder (tazarotene induced) 3Predicted intracellular proteins
Predicted membrane proteins
Pancreatic cancer: 6.26e-6
Breast cancer: 1.35e-5
Cervical cancer: 4.00e-4
Expressed in all
MMP28Matrix metallopeptidase 28Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Pancreatic cancer: 6.28e-6
Tissue enhanced
EIF2AEukaryotic translation initiation factor 2A, 65kDaPlasma proteins
Predicted intracellular proteins
Mitochondria
Cytosol		Pancreatic cancer: 6.57e-6
Liver cancer: 2.36e-5
Expressed in all
RPERibulose-5-phosphate-3-epimeraseEnzymes
Predicted intracellular proteins
Liver cancer: 1.42e-6
Pancreatic cancer: 7.00e-6
Expressed in all
ERGIC2ERGIC and golgi 2Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Nucleoli
Vesicles		Renal cancer: 3.76e-6
Pancreatic cancer: 7.02e-6
Liver cancer: 8.06e-6
Ovarian cancer: 8.18e-4
Expressed in all
B3GNT5UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5Enzymes
Predicted intracellular proteins
NucleoliRenal cancer: 1.30e-7
Pancreatic cancer: 7.23e-6
Liver cancer: 5.09e-4
Expressed in all
LDHALactate dehydrogenase ACancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Vesicles
Cytosol		Renal cancer: 9.69e-9
Liver cancer: 3.26e-8
Lung cancer: 2.27e-6
Pancreatic cancer: 8.09e-6
Cervical cancer: 2.78e-5
Expressed in all
IPO7Importin 7Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Transporters
Nucleoplasm
Cytosol		Pancreatic cancer: 8.38e-6
Cervical cancer: 4.98e-4
Liver cancer: 6.57e-4
Expressed in all
ANXA2Annexin A2Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Transporters
Renal cancer: 2.11e-6
Pancreatic cancer: 8.47e-6
Liver cancer: 2.54e-5
Urothelial cancer: 6.59e-5
Endometrial cancer: 6.88e-5
Lung cancer: 7.51e-4
Expressed in all
CDCA5Cell division cycle associated 5Predicted intracellular proteins
NucleoplasmRenal cancer: 0.00e+0
Liver cancer: 8.21e-6
Pancreatic cancer: 8.72e-6
Endometrial cancer: 2.67e-4
Tissue enhanced
VPS26AVPS26 retromer complex component APlasma proteins
Predicted intracellular proteins
Endosomes
Lysosomes		Liver cancer: 1.70e-6
Pancreatic cancer: 9.18e-6
Head and neck cancer: 1.72e-4
Expressed in all
HIST1H3HHistone cluster 1, H3hPredicted intracellular proteins
Pancreatic cancer: 9.25e-6
Renal cancer: 5.73e-5
Cervical cancer: 4.35e-4
Mixed
KIF4AKinesin family member 4APredicted intracellular proteins
Nucleoplasm
Cytokinetic bridge		Liver cancer: 7.37e-6
Pancreatic cancer: 9.44e-6
Mixed
DLGAP5Discs, large (Drosophila) homolog-associated protein 5Plasma proteins
Predicted intracellular proteins
Microtubule organizing center
Cytosol		Liver cancer: 1.52e-6
Pancreatic cancer: 9.94e-6
Endometrial cancer: 4.59e-4
Lung cancer: 7.85e-4
Tissue enhanced
ITGA2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)Cancer-related genes
CD markers
Plasma proteins
Predicted membrane proteins
Nucleus
Cytosol		Pancreatic cancer: 1.02e-5
Mixed
SERP1Stress-associated endoplasmic reticulum protein 1Predicted intracellular proteins
Predicted membrane proteins
Endoplasmic reticulumPancreatic cancer: 1.03e-5
Expressed in all
PERPPERP, TP53 apoptosis effectorPredicted membrane proteins
Pancreatic cancer: 1.05e-5
Lung cancer: 3.73e-4
Breast cancer: 5.46e-4
Group enriched

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The Human Protein Atlas

The Human Protein Atlas project is funded
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